In what direction are the peptides synthesized? August 15, 2019 06:13 Peptides are synthesized from the C-terminus to the N-terminus of the sequence. Related articles What if there is a problem with the synthesis of my peptide? What is the maximum peptide length you can produce? What is the Boc strategy in SPPS? What's the conditions you use to deprotect and release the peptide from the resin? What methods do you use to synthesize peptides?